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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11775 | KRAS inhibitor-8 | Ras | |
KRAS inhibitor-8 is a potent KRAS G12C inhibitor. | |||
T9585 | GNE-9815 | 3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide | Raf |
GNE-9815 (3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide) is a high kinase-selective inhibitor of RAF and targets KRAS-mutant cancers through combina... | |||
T74663 | KRAS G12D inhibitor 17 | ||
KRAS G12D Inhibitor 17 (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC) [1], specifically inducing degradation of the G12D-mutation KRAS protein. |